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Mitochondrial dysfunction, protein misfolding and neuroinflammation in parkinsons disease: roads to biomarker discovery

She H, Zhu Y, Deng H, Kuang L, Fang H, Zhang Z, et al

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For instance, palmitic acid supplementation does not rescue the cell proliferation defect observed in CIC KO or BTA-treated cells, suggesting that the defect is due to increased ROS levels and loss of mitochondrial membrane potential, which can be rescued by N-acetyl cysteine (NAC) [61]

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Finally, multivariable Cox regression analysis revealed that GSTM3 was a risk factor for OS among patients with PC (hazard ratio [HR] = 1.208, 95% confidence interval [CI]: 1.0221.608, P = 0.012) (Table 2)