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Toxicol Appl Pharmacol 257(3):349355 Huidobro C, Martn-Vicente P, Lopez-Martinez C, Alonso-Lpez I, Amado-Rodriguez L, Crespo I, Albaiceta GM (2021) Cellular and molecular features of senescence in acute lung injury

Antioxidant genes in oxidative stress Antioxidants neutralize excess free radicals, protecting cells and contributing to disease prevention ( 2 - into H 2 O 2, which is then transformed into water (H 2 O) and oxygen (O 2 ) by CAT or GPx

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High levels of 150-kDa insulin-like growth factor binding protein three ternary complex in patients with acromegaly and the effect of pegvisomant-induced serum IGF-I normalization

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Toxic bile salts retention in the liver is accompanied by intracellular metabolic disorders, inflammation and reduced detoxification capacity [176], which may enhance the generation of oxidative stress and the accumulation of ROS and RNS in hepatocytes [177], leading to generalized systemic damage to major organs, starting from the liver and reaching the brain, heart, intestine, and kidney [178,179,180]