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TRT is approved to treat male hypogonadism and it can increase testosterone levels (and help manage symptoms of low T) regardless of the subject's medical condition and comorbidities [13]
The role of tumor-associated macrophage in breast cancer biology

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On the other hand, non-enzymatic antioxidants include glutathione (GSH), vitamins (such as vitamin C and vitamin E), selenium, and metabolites (including bilirubin and melatonin)

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Therefore, cancer cells may be more susceptible to ALT activation due to the binding of epitalon to the already reduced levels of histone H1, whereas normal cells may be more resilient as they naturally express higher levels of H1
