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The direct intranasal drug delivery approach to therapeutics holds great promise for the treatment of central nervous system (CNS) disorders, as this route is non-invasive, bypasses the BBB, enhances the bioavailability, facilitates drug dose reduction, and reduces adverse systemic effects

It has been used in peer-reviewed studies, including a 2019 publication where it was applied to stain L-Glutamate in human iPSC-derived neurons

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