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Although the cause of hair loss is not yet fully understood, there are many underlying factors that are shown to be associated with the loss of function of our hair follicles as we age

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Further, we discuss the therapeutic approaches targeting NF-B signaling, including IKK inhibitors, monoclonal antibodies, proteasome inhibitors, nuclear translocation inhibitors, DNA binding inhibitors, TKIs, non-coding RNAs, immunotherapy, and CAR-T