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For example, gut-microbiota-derived metabolite trimethylamine N -oxide (TMAO) from dietary choline, carnitine, and L -carnitine can aggravate hepatic steatosis in NAFLD by regulating BA metabolism through the regulation of farnesoid X receptor (FXR) signaling pathway [63]

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence

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2018;115:E147584

Data availability The shotgun metagenomics dataset generated during this study (i.e., NovaSeq X Plus Series paired-end 150 fastq reads) can be found in the European Nucleotide Archive repository at: with accession number PRJEB85873.The remaining datasets used and/or analyzed during the current study are included in the manuscript or supporting files