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Notably, elevated TMAO concentrations induce oxidative stress and activate the NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome in human fetal colon cells, suggesting that TMAO triggers inflammasome activation and promotes an inflammatory response in the intestinal endothelium (17)

Gardner A, Boles R

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Sodium Hydrosulphide Restores Tumour Necrosis Factor--Induced Mitochondrial Dysfunction and Metabolic Dysregulation in HL-1 Cells

In addition, the quality of the vitelline membrane declines, making the yolk more breakable

10.26444/jpccr/141582