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Lancet 2:632, 1977 Thompson J, Greeley GH Jr, Rayford PL, Twonsed CM Jr: Gastrointestinal Endocrinology

A recombinant form of human G-CSF, specifically the recombinant methionyl human G-CSF NEUPOGEN (filgrastim), was initially approved with an indicated use to decrease the incidence of infection and reduce severe neutropenia

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The serum was diluted with SA buffer (about 300 L) and analyzed for biochemical indices using the Hitachi 7,060 automatic analyzer, measuring AST, ALT, ALP, T-Bil-V2, UREA, and CREA-S