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Half of the taken tissues were placed in a 10% formaldehyde solution for histopathological and immunohistochemical analyses, while the remaining tissues were wrapped in aluminum foils and stored at 80 C for genetic and biochemical analyses

DMF is an ester of fumaric acid and following its administration, DMF is converted to monomethyl fumarate (MMF) which then upregulates the NRF2 pathway