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Hierarchical clustering analysis was performed to visualize relative differences in metabolite abundance between groups (Fig

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studies in skinned single cardiomyocytes linked this phosphorylation to an increase in the cross-bridge cycling rate and a reduction in myofilament calcium sensitivity ( 23 /Ser 24 and Thr 144 ) and it also phosphorylates a number of threonine phosphorylation sites on cTnT during oxidative stress when the enzyme is Tyr 311 -phosphorylated by Src

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