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However, to ensure confidence and fewer false positives, a positive threshold of MFI 1,031 was chosen for analyses

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This regulatory pathway appears to be conserved in humans and nonhuman primates, since circulating FGF19 levels inversely correlate with markers of hepatic bile acid biosynthesis, administration of inhibitory anti-FGFR4 antibodies stimulated bile acid synthesis in nonhuman primates, and administration of recombinant FGF19 to human subjects strongly repressed bile acid synthesis

The multifaceted role of autophagy in cancer

Epub 2020 Apr 24

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