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This patient's primary issue is a lack of central dopamine causing motor freezing, and inhibiting its conversion to norepinephrine would not alleviate these extrapyramidal symptoms

10.1101/gad.13.1.76 64 JaganjacM.MilkovicL.ZarkovicN.ZarkovicK

doi: 10.1016/j.biotechadv.2021.107794 33 Chvez-CabreraC.Flores-BustamanteZ

Among ascorbic acid derivatives, fatty acid esters of ascorbic acid viz., ascorbyl palmitate and ascorbyl stearate have attracted considerable interest as anticancer compounds in view of their lipophilic nature as they can easily cross cell membranes and blood brain barrier [76]

(2002) mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery, Cell , 110 , 163-175, Ichimura, Y., Waguri, S., Sou, Y.-S., Kageyama, S., Hasegawa, J., Ishimura, R., et al

Neutrophil/lymphocyte ratio is an independent prognostic factor in elderly patients with high-grade gliomas