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Notably, despite the induction of pain following acute TRPV1 activation by agonists such as capsaicin, prolonged/repeated stimulation has been shown to lead to receptor desensitization with analgesic effects (Gao et al., 2024)

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doi: 10.1111/cns.12059 [DOI] [PMC free article] [PubMed] [Google Scholar] 202

Ibuprofen Protects Dopaminergic Neurons Against Glutamate Toxicity In Vitro

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