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Evidence-based management focuses on lifestyle modification, weight loss, and treatment of underlying metabolic dysfunction

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[DOI] [PMC free article] [PubMed] [Google Scholar] 449.Brgeson E., McGillicuddy F.C., Harford K.A., Corrigan N., Higgins D.F., Maderna P., Roche H.M., Godson C

In this regard, complementary and alternative therapies, which are generally not patentable and have little potential for producing large economic gain, are generally disregarded in favor of new designer drugs or old reworked protocols