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These models have been used to evaluate: soft-tissue and connective-tissue injury responses tendon and ligament healing environments experimentally created muscle injuries gastrointestinal integrity and inflammatory responses nerve-lesion and neuroinflammatory pathways Outcomes vary depending on dosage, timing, delivery route, and the nature of the injury model

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NLRP3 expression was significantly increased in the synoviocytes of OA mice compared with SHAM controls

Theranostics 13 , 28792895 (2023)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Boso M, Emanuele E, Minoretti P, et al