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Importantly, several large-scale meta-analyses of genome-wide association studies revealed that this inactivating mutation is strongly associated with type 2 diabetes 9 , body mass index 10 , and serum lipids 11 in East Asians

To further examine the role in the catalytic reaction, kinetic analyses were performed using various concentrations of the donor and acceptor substrates (Fig

77 Hyperlipidemia Hyperlipidemia is characterized by the abnormal elevation of one or more lipid components in plasma, resulting from disruptions in lipid metabolism or transport

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Therefore, more studies are needed to confirm whether the ketone body type significantly alters MASLD outcomes and mitochondrial function

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