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BPC 157 therapy counteracted both the MDA-value increase as well as the oxidative stress damages in all organs tested at the end of all decompression/reperfusion periods, which were investigated to provide additional proof for the concept (Table 4)

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Clinical improvement was also observed in oxidative stress markers, with improvements in methionine levels (p=0.05), homocysteine levels (SAH, p=0.007) and the ratio of S-adenosylmethionine (SAMe) to SAH (p=0.007), indicating improvement with methylation at the cellular level and a decrease in oxidative stress in the body 2

Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination

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