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Long-term human safety data is limited for both

Applying normal to a sick population is not acting in the best interests of the patient, this drop in the new normal cannot reflect evolutionary change

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10.1007/s11064-019-02729-0 69 KlopB.ElteJ.CabezasM

The most common sites for tirzepatide are: Abdomen (2 inches away from the navel, rotating sides) Front of thighs (upper third, alternating legs) Back of upper arms (harder to self-administer) Rotate injection sites with every dose