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Interestingly, one proposed PH domain binding site is not surface exposed in structural models of PLC, with binding of G proposed to be mediated by dynamic dissociation from the PLC core, leading to exposure of the G-binding surface on the PH domain (Kadamur and Ross, 2016)

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N-glycosylation at Asn78 of GPIHBP1 is required for its intracellular trafficking as replacing Asn78 to Gln leads to ER retention [36]

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In uno studio, 2 grammi di acetil-L-carnitina al giorno per 24 settimane hanno provocato un calo di quasi 10 punti della pressione arteriosa sistolica 48