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In fact, IGF-1 acts on several different tissues (not just muscle) to enhance growth through various mechanisms

Although the cerebrovascular system plays an important protective role in maintaining the internal environment balance necessary for neuronal function, the BBB also prevents the entry of drugs, making CNS diseases more difficult to treat than those that can be reached by the systemic circulation
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Developed in the 1990s, ipamorelin was the first peptide in its class shown to release growth hormone this selectively
