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598 Tissue-resident T cells exhibit metabolic profiles similar to those of proinflammatory macrophages, which utilize nuclear PKM2/STAT3 signaling to maintain persistent IL-1 and IL-6 production

Modulating mitochondrial function by dampening pathways such as those driven by Akt may increase the efficacy of therapies based upon adoptive transfer of tumoricidal T cells

USD 39.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Data availability Mass spectrometric data are available at the ProteomeXchange Consortium ( with dataset identifier PXD010174

J.HowellB

The overlap in genes differentially regulated by the two conditions was actually bigger (data not shown)

Stugiewicz, M