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4 Treatment There is no cure for RLS, but a number of non-pharmacologic and pharmacologic therapies have been found to be helpful in its management

This process, which ensures an adequate supply of free CoA, is essential for the oxidation of pyruvate and helps to coordinate pyruvate dehydrogenase activity with the rate of glycolysis, thereby maintaining the bodys ability to switch between fat and carbohydrate as the main energy substrate [9]
