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Before the ketogenic diet can be considered as a therapeutic option, it is important to establish with greater certainty that there is a reliable symptomatic benefit: which symptoms or groups of symptoms are impacted (if non-motor symptoms, which ones, and by which mechanism), what timescale is needed to obtain benefit, and how large an effect size can be achieved
The term of drug-tolerant persister (DTP) cells has been employed to explain the non-genetic alterations-associated drug-tolerance
The sugar water test (sucrose hemolysis test) and the Ham test (acidified serum lysis test) have insufficient sensitivity for diagnosis of PNH and have been replaced by flow cytometric techniques
[DOI] [PubMed] [Google Scholar] 563.Holm L, Cassidy JD, Carroll LJ, Borg J
however, these therapies can carry a considerable burden of long-term adverse effects
