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Current Good Manufacturing Practice (CGMP) failures also included weak oversight of quality units, poor equipment and room-cleaning systems, inadequate smoke studies, and incomplete batch records

Electrophilic agents and antioxidants induce conformational changes in Keap1, thus impeding the binding with Nrf2 leading to the consequent migration of the nuclear factor in the nucleus, where it can exert its function [22]

May 1986;4(2):223-233

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