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Nature 386 , 292296 (1997)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Salama A, Fayed HM, Elgohary R

How Melanotan Works & Dosing Tips Reconstitution : 10 mg vial + 5 mL bacteriostatic water = 2000 mcg/mL concentration Administration : Subcutaneous injection (typically belly fat area) Start : 10 units (200 mcg) daily for 12 weeks Maintenance : 5 units (100 mcg) 23x/week Store in refrigeration after mixing Important Notes: Results vary individually Adjust maintenance dosing for desired tan level Always wear SPF and limit sun exposure despite tanning benefits Benefits Beyond Tanning Shared by Both Melanotan I & II: Enhanced melanin production Photoprotection (UV defense) Immune system support Potential benefits for autoimmune conditions Specific to Melanotan II: Appetite suppression (supports weight management) Lipolysis (fat burning) Improved glucose and cholesterol metabolism Libido enhancement (dose-dependent) Melanotan II is sometimes used off-label as a libido booster or fat-loss peptide due to these effects

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