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Similar to other reports, our cases with NCM had the symptoms related to increased intracranial pressure resulting from the obstruction of the ventricular system foramen, subarachnoid cistern, or arachnoid granulations secondary to melanocytic proliferations ( There is no effective therapy in modifying the course of the disease, however, MEK inhibitors are under experimental evaluation ( Clinical follow-up of CMN in children includes MRI screening when the CMN is defined as large-giant, being multiple satellites, and located in the posterior axis areas, even with no obvious CNS symptoms

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After that we planned for surgical excision and skin grafting for ulcerated plaque, but she refused the surgery

Yeast cells were first identified based on forward scatter area (FSC-A) versus side scatter area (SSC-A) characteristics (left), followed by exclusion of doublets by gating on single cells using FSC-A versus forward scatter height (FSC-H) (middle), and the resulting single cell population was then analyzed for Rhodamine and Alexa 647 fluorescence (right)

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