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To summarize, 2D cell models of cell lines are the easiest to handle and most reproducible models for in vitro toxico-metabolomic studies

Martelli et al., 2020a), e.g., polysaccharides from algae are already recognized and accepted as dietary prebiotics (Jimnez-Escrig et al., 2001

The two systems work together to preserve cell homeostasis by destroying unnecessary and damaged proteins and regulating the cell cycle, DNA transcription, and translation

In the ND region, only GLCM contrast, homogeneity, and correlation displayed a main effect of time

HEPATOCYTE CELL DEATH MECHANISMS AFTER APAP TOXICITY The mode of cell death after APAP-induced liver injury was controversial initially, since a number of mechanistic steps in the process, such as mitochondrial Bax translocation, release of cytochrome c64,79,88, and nuclear DNA fragmentation32, were similar to that seen during apoptosis (Fig

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