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Through the activation of HCAR2, BHB also can attenuate inflammatory responses in various cell types, including macrophages and endothelial cells, thereby potentially reducing the risk of chronic inflammatory diseases [132,133]

I6P7 peptide modified superparamagnetic iron oxide nanoparticles for magnetic resonance imaging detection of low-grade brain gliomas

Source: INCI, MychelleDermaceuticals.

Thus, defects in this enzyme may lead to severe metabolic disorders, including alkaptonuria, phenylketonuria and tyrosinaemia, and new discoveries may allow the enzyme to protect against certain diseases related to oxidative stress