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Numerous studies have found the exact role of glutathione in the development of AMD

- Lithium: because it reduces the renal clearance and increases lithium levels in plasma which increases the risk of lithium toxicity
[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Girgis H, Palmier B, Croci N, Soustrat M, Plotkine M, Marchand-Leroux C

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This effect appears to be enhanced when EGCG is combined with caffeine

47,59,60 This created controversies regarding the roles of reactive oxygen and LPO in the pathophysiology
