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Consistent inhibition of S6K1 activity in peripheral blood mononuclear cells was seen with doses 20 mg per week and was sustained for at least 7 days at doses 20 mg per week (O'Donnell et al, 2008)

4-HNE serves as both a substrate for ALDH2 and an inhibitor of its activity

doi: 10.1152/physiolgenomics.00081.2016 4 AfsarB.VaziriN

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Bakun P, Mlynarczyk DT, Koczorowski T, Cerbin-Koczorowska M, Piwowarczyk L, Kolasiski E, et al

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