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Description

Larsen, Anna T

4.2 Active targeting strategy The active targeting strategy does not rely on the inherent transport mechanisms of the BBB, but instead actively regulates or enhances specific transport pathways through targeted design, thereby improving the efficiency and specificity of drug delivery to the brain (Table 1)

Glaucomatous rats presented with severe retinal damage and failed function were rats with permanent venous congestion and permanently increased intraocular pressure induced by cauterization of three of four episcleral veins (open-angle glaucoma model) [116,117,118,119,120,121]

With aging, the brains ability to use oxygen gradually decreases, which leads to the development of a range of neurological diseases, such as neurodegenerative diseases [6]

The formulations or compositions are administered via cannula and/or injection, via a drop dispenser, as a spray in the ear canal, or as a paint via a cotton tipped stick