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Nrf2/are pathway negatively regulates bace1 expression and ameliorates cognitive deficits in mouse alzheimers models

Klicek, R., Sever, M., Radic, B., Drmic, D., Kocman, I., Zoricic, I.,

Partial purification, specificity and mechanism of action of the nisin-inactivating enzyme from Bacillus cereus

et alXiaohua Zhang, MD2,3

The key proteins mediating mitochondrial fusion include mitofusins 1 and 2 (MFN1/2) located on the outer mitochondrial membrane (OMM) and optic atrophy 1 (OPA1) on the inner mitochondrial membrane (IMM)

Available data suggest that the inadequate ability to activate thermoregulatory cooling mechanisms, as indexed by a reduced ability to sweat, may play an important role in the body temperature alterations observed in depression 15,31