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doi: 10.1074/jbc.M002965200 [DOI] [PubMed] [Google Scholar] 62

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The study revealed that inhibition potency increased with longer polyethylene glycol chains, likely due to their ability to interact with multiple organic cationic transporter receptors simultaneously

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PMID: 116 OkoyeochaEVredevoogdNPaithankarSMasinoBAnantharamPGoswamiDet al

Rather, their compounds are more stable due to their cyclically constrained constriction
