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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

inhibition has been shown to reduce adipose mass in diet-induced obese mice

Their usage must strictly follow dosage specifications, administration methods, and relevant precautions, balancing convenience and safety to ensure their effects on metabolic regulation and assisted body composition management

In the context of obesity research, Adipotide has demonstrated the ability to cause rapid, significant weight loss in rhesus monkeys and rodents by literally destroying the tissue structure of fat deposits

PMID: 24717514 View source Ulanovskaya OA, et al

However, they will not disappear from the market when AAS are still used