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Metabolism abnormalities induced by exposure to excessive UA are important factors mediating the pathological development of HUA-associated multiple organ complications ( via UA excretion agent benzbromarone therapy ( via regulating transforming growth factor 1, nicotinamide adenine dinucleotide phosphate oxidase and AMP-activated protein kinase mediated reactive oxygen species and inflammation (Madlala et al., 2016

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Carnitines increase plasma levels of adenosine and ATP in humans Vasc Med 1997

Neurobiol Dis 170:105766 [DOI] [PMC free article] [PubMed] [Google Scholar] 52.Hoglund E, Overli O, Winberg S (2019) Tryptophan metabolic pathways and brain serotonergic activity: a comparative review

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