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You may want to talk with a doctor about B12 shots if you regularly experience: Persistent fatigue and lethargy Muscle aches and joint pain Loss of appetite Nausea, constipation, diarrhea, or cramping Poor memory or difficulty concentrating Mood swings Can B12 Injections Help With Mood Enhancement and Mental Clarity

If skin irritation occurs, discontinue use

In stark contrast, the placebo group experienced a slight deterioration in vascular function over the same period

The other items on this list fall under this principle as well
