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For teeth with complex canal anatomy, previous failed root canals, or persistent infection, adding laser assisted disinfection to the protocol can be the difference between success and retreatment

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More research is needed to confirm this

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However, adjunctive amlodipine therapy provided objective improvement in cardiac iron overload on imaging and symptomatic improvement in functional status for this patient

Simultaneously, LBPs activated the PI3K/Akt/mTOR pathway, and Nrf2/HO-1 pathway, whereas inhibited the AGEs-RAGE signalling pathway to mitigate OS (Li, 2007
