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On rectal examination, sphincter tone was good, rectal was collapsed, there was no tumor, uterus and adnexa were within normal limit and there was no fecal material

doi: 10.3389/fimmu.2022.874490 89 BaldiSPagliaiGDinuMPallecchiMDanzaGBenedettelliSet al

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However, long-term data are limited, and most of the current literature surrounding curcumin suggests that performance and recovery benefits are observed only with short-term supplementation [290]

We also found that the copper level was upregulated in the normal rat kidney fibroblastic cell line (NRK-49F) and the normal rat kidney proximal tubular cells (NRK-52E) when treated with TGF-1, the major mediator of renal fibrosis 12,13 (Fig