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Clinical research has shown that subjects experience reductions in body fat percentage without corresponding losses in muscle tissue

Statements Data availability statement The datasets generated for this study are available on request to the corresponding author

Journal Clinical Nutrition 91 (3), 571577

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Methods We queried the PubMed, Cochrane, and Embase databases to identify prospective RCTs using inclusion criteria: 1) patients diagnosed with IC, 2) interventions included relevant treatments, 3) comparisons were a specified control or placebo, 4) outcomes were mean differences for individual symptoms and structured questionnaires

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