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Mechanistically, GSTZ1 depletion enhanced the activation of the Nrf2 pathway and increased the GPX4 level, thereby suppressing sorafenib-induced ferroptosis (Wang Q

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OZiva published a clinical study claiming 90.6% of participants saw brighter skin in 8 weeks

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Most of these trials have primarily assessed its safety, tolerability, pharmacokinetics, and bioavailability, while only a few have specifically investigated its efficacy in treating specific types of cancer (121)

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