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B12 is a vitamin found in a variety of foods, such as fish, meat, eggs, and other dairy products

Cardiovascular Risks: Use with caution in patients with a history of cardiac conditions as lidocaine can affect cardiac function

If youre at risk for a vitamin B12 deficiency, you may want to ask your provider to check your vitamin B12 levels if you are pregnant or thinking of becoming pregnant

What remains unknown Despite encouraging data, genuine unknowns exist: Effects beyond 6-9 months of continuous use have not been formally studied in animals or humans

This method is often used at the start of treatment or for severe symptoms

Peer review Peer review information Nature Communications thanks the anonymous reviewer(s) for their contribution to the peer review of this work