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Mechanism [edit] Glutathione synthase catalyzes the chemical reaction ATP + gamma-L-glutamyl-L-cysteine + glycine ADP + phosphate + glutathione The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and glycine, whereas its 3 products are ADP, phosphate, and glutathione

a tlzott stressz miatt szervezetnkben a glutation termszetes termelse tmenetileg korltozott

For instance, berberine inhibits endothelial ferroptosis and AS by suppressing ACSL4 expression (Hong et al., 2024)

Cable, D

This review provides an overview of the GSH transporter and the status of GSH transporter-based brain targeting drug delivery systems with the intention of bringing the field to the attention of a medicinal chemist for his/her expertise in organic synthesis, ligand identification and optimization