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Upon membrane binding, the Syn N-terminal region undergoes a disorder-to-order transition and adopts an -helical conformation, while the acidic C-terminal tail remains disordered 79,80

Oncotarget, 7 (16), 2292822938

While proteasomal dysfunction is correlated with age progression and protein aggregation, proteasome activation slows the aging progress down and increases longevity (Saez and Vilchez, 2014)

ErbB2 deregulates breast cancer cell mitotic exit and induces taxol resistance through upregulation of survivin

7 common vitamin and mineral deficiencies that impact metabolic health Vitamin and mineral deficiencies are less common in the United States and developed countries than in countries lacking access to safe, quality food and healthcare---but they're still surprisingly prevalent

Gopalai, A