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We are conscious of the limitations of the animal models [123], however in a clinical trial undertaken by this group to asses IGF-1 in liver function under cirrhosis with these same dosage (20 g/kg/day) no side effects were reported and liver function greatly increased [108]
The importance of its presence or non-presence in a purely plant-based diet should definitely be emphasized

The primary storage unit for vitamins such as A, D, E, K, and B12 is the liver
Pull up the volume of bacteriostatic water from the table above

2) it induces higher folate concentration within a shorter time in the blood stream, so it works faster and takes effect earlier
Digestive issues such as Crohn's or celiac disease can lead to impaired absorption of nutrients in the gut which may result in the need for B12 supplementation
