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The constructed pURA3-GSH1 strain was heterozygous at the GSH1 locus, with one allele expressing the URA3 ORF under pGSH1 control and the other expressing GSH1 under pTEF1 control (FigureS1 A )

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As fixed effects we added time and treatment-dose effects with interaction

Why CagriSema Costs More Than Semaglutide Alone A natural question: if CagriSema is "semaglutide plus cagrilintide," why isn't the price simply C$65 (semaglutide) plus a small premium for the cagrilintide