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Even if methylation is still slightly impaired after optimizing #1 and #2, B6 opens a second exit for homocysteine

Cesar LB, Gojkovic S, Krezic I, et al

Over-diluting creates larger volumes that must be stored longer, increasing degradation exposure

References Haffner D, Schaefer F, Nissel R, Wuhl E, Tonshoff B, Mehls O (2000) Effect of growth hormone treatment on the adult height of children with chronic renal failure

For GHK-Cu discussions, the abdomen is usually the first site people mention because it is easier to keep spacing consistent