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Thus, TNBS promotes two independent mechanisms of injury, GSH depletion and ROS generation, both being required for the manifestation of mucosal injury as GSH limitation renders intestine susceptible to the TNBS-induced ROS overgeneration

Simethicone may interfere with the effect of some reagents used in diagnostics, such as guaiac gum.

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Another high-risk group includes people over age 60 who have decreased absorption of vitamin B12 from food or pills

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