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however, it may be associated with severe side effects including sedation, hallucinations and cardiac instability limiting its use in outpatient settings [107, 108, 376]

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However, it is a challenging standpoint to offer a therapy that can work for the whole society

Recently, blood-based biomarkers including ctDNA, CTCs, and miRNA signatures have emerged as promising non-invasive tools for early diagnosis, minimal residual disease monitoring, and recurrence prediction (324)

[DOI] [PMC free article] [PubMed] [Google Scholar] Hasanuzzaman M, Nahar K, Anee TI, Fujita M

Colman, H
