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This selectivity was observed in animal models and has not been fully established in long-term human studies

10.1073/pnas.1516953113 Proc

[DOI] [PubMed] [Google Scholar] 40.Gamble L.J., Boesch J.M., Frye C.W., Schwark W.S., Mann S., Wolfe L., Wakshlag J.J

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In addition, recent data have implicated the aryl hydrocarbon receptor (AhR) in many aging-linked conditions (Salminen, 2022)

Tesamorelin is best suited for individuals needing targeted visceral fat reduction, particularly those with HIV-associated lipodystrophy or significant abdominal fat accumulation for overall metabolic health