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Deficiency causes fatigue, reduced stamina, brain fog, and low mood, all of which make it harder to exercise and make healthy food choices

The 2002 Leyden et al

This being said many of the studied benefits of ALA are only associated with high dose intravenous therapy

Medications can alter metabolism, stomach acid, and gut bacteria in ways that prevent normal absorption of B vitamins from food and traditional supplements

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Are these supplements safe for long-term use